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\u3000\u3000\u5982\u679c\u662f\u6709\u9ad8\u7518\u6cb9\u4e09\u916f\u8840\u75c7\uff0c\u53ef\u4ee5\u5728\u533b\u751f\u7684\u6307\u5bfc\u4e0b\u670d\u7528\u9c7c\u6cb9\u8fdb\u884c\u8c03\u8282\u3002<\/p>\n\n\n\n

\u3000\u3000\u7b2c\u4e8c\uff0c\u9c7c\u6cb9\u4e2d\u7684 DHA \u548c EPA \u5bf9\u5a74\u5e7c\u513f\u7684\u795e\u7ecf\u53d1\u80b2\u548c\u89c6\u529b\u53d1\u80b2\u6709\u76ca\u3002<\/p>\n\n\n\n

\u3000\u3000\u6211\u56fd\u6700\u65b0\u7248\u300a\u4e2d\u56fd\u5c45\u6c11\u81b3\u98df\u8425\u517b\u7d20\u53c2\u8003\u6444\u5165\u91cf\u300b(DRIs)\u8ba4\u4e3a\uff0c\u5b55\u671f\u6bcf\u5929DHA+EPA\u7684\u9002\u5b9c\u6444\u5165\u91cf\u4e3a250mg\uff0c\u5176\u4e2dDHA\u81f3\u5c11200mg\uff1b\u800c\u5bf9\u4e8e\u4e0d\u540c\u5e74\u9f84\u9636\u6bb5\u5b69\u5b50\u6765\u8bf4\uff0c\u6bcf\u5929\u7684DHA\u9002\u5b9c\u6444\u5165\u91cf\u662f100-250\u6beb\u514b[12]\u3002<\/p>\n\n\n\n

\u3000\u3000\u81f3\u4e8e\u5176\u4ed6\u7684\u5065\u5eb7\u529f\u6548\uff0c\u76ee\u524d\u7684\u79d1\u5b66\u8bc1\u636e\u90fd\u6bd4\u8f83\u5c11\uff0c\u5927\u5bb6\u53ef\u5343\u4e07\u4e0d\u8981\u628a\u5b83\u5f53\u4f5c\u9884\u9632\u75be\u75c5\u7684\u4e07\u80fd\u6cb9\u4e86\u3002<\/p>\n\n\n\n

\u5230\u5e95\u8981\u4e0d\u8981\u5403\u9c7c\u6cb9\uff1f<\/strong><\/p>\n\n\n\n

\u3000\u3000\u5148\u8bf4\u7ed3\u8bba\uff1a\u5982\u679c\u65e0\u6cd5\u4fdd\u8bc1\u6bcf\u5468\u98df\u7528300-500\u514b\u9c7c\u867e\u7b49\u6c34\u4ea7\uff0c\u53ef\u4ee5\u9009\u62e9\u8865\u5145\u9c7c\u6cb9\u3002<\/p>\n\n\n\n

\u3000\u3000DHA\u3001EPA\u7b49n-3\u8102\u80aa\u9178\u5bf9\u5065\u5eb7\u786e\u5b9e\u662f\u6709\u76ca\u7684\uff0c\u800c\u4e14\u6c34\u4ea7(\u9c7c\u7c7b\u3001\u867e\u7c7b\u548c\u8d1d\u7c7b)\u6709\u76ca\u7684\u8bc1\u636e\u6bd4 \u03c9-3 \u8102\u80aa\u9178 \u8865\u5145\u5242\u7684\u8bc1\u636e\u66f4\u6709\u529b\uff0c\u6c34\u4ea7\u4e2d\u9664\u4e86\u03c9-3\u8102\u80aa\u9178 \u4e4b\u5916\u7684\u5176\u4ed6\u8425\u517b\u6210\u5206\u4e5f\u53ef\u80fd\u53d1\u6325\u5176\u76ca\u5904\uff0c\u5403\u6c34\u4ea7\u7684\u4eba\u901a\u5e38\u751f\u6d3b\u65b9\u5f0f\u66f4\u5065\u5eb7[13]\u3002\u56e0\u6b64\uff0c\u60f3\u8981\u83b7\u5f97DHA\u3001EPA\uff0c\u6700\u4f73\u7684\u9014\u5f84\u4f9d\u7136\u662f\u98df\u7269\u3002<\/p>\n\n\n\n

\u3000\u3000\u9c7c\u867e\u7b49\u6c34\u4ea7\u54c1\u4e2d DHA \u662f\u6700\u4e30\u5bcc\u7684\uff0c\u8fd8\u80fd\u63d0\u4f9b\u4f18\u8d28\u86cb\u767d\u3001\u7ef4\u751f\u7d20 A\u3001\u94c1\u3001\u950c\u7b49\u5fae\u91cf\u8425\u517b\u7d20\uff0c\u5982\u679c\u6761\u4ef6\u5141\u8bb8\uff0c\u6bcf\u5929\u5403\u70b9\u9c7c\u867e\u5f53\u7136\u662f\u6700\u597d\u7684\u3002\u6211\u56fd\u81b3\u98df\u6307\u5357\u5efa\u8bae[14]\uff0c\u6210\u5e74\u4eba\u5e73\u5747\u6bcf\u5929\u6444\u5165\u603b\u91cf120~200g\uff0c\u76f8\u5f53\u4e8e\u6bcf\u5468\u5403\u9c7c2\u6b21\u6216300~500g\u3002\u5b55\u671f\u53ef\u4ee5\u9002\u5f53\u589e\u52a0\uff0c\u6bcf\u5468\u81f3\u5c112-3\u6b21\u9c7c\u7c7b\u3002\u6b64\u5916\uff0c\u7d2b\u82cf\u6cb9\u3001\u4e9a\u9ebb\u7c7d\u6cb9\u4e2d\u03b1-\u4e9a\u9ebb\u9178\u4e5f\u53ef\u4ee5\u8f6c\u5316\u6210\u03c9-3\u8102\u80aa\u9178\uff0c\u5e73\u65f6\u4e5f\u53ef\u4ee5\u6362\u7740\u5403\u3002<\/p>\n\n\n\n

\u3000\u3000\u4e0d\u8fc7\u6211\u56fd\u4f9d\u7136\u6709\u5f88\u591a\u5c45\u6c11\u6c34\u4ea7\u54c1\u5403\u5f97\u6bd4\u8f83\u5c11\uff0cDHA\u548cEPA\u7684\u6444\u5165\u91cf\u666e\u904d\u504f\u4f4e\u3002\u6bd4\u5982\uff0c\u5b55\u5410\u53cd\u5e94\u6bd4\u8f83\u4e25\u91cd\u7684\u4eba\uff0c\u5728\u5b55\u671f\u5403\u9c7c\u867e\u53ef\u80fd\u4e0d\u662f\u4ef6\u5bb9\u6613\u7684\u4e8b\uff1b\u7ed9\u5b69\u5b50\u505a\u9c7c\u867e\u5403\uff0c\u8d39\u65f6\uff0c\u8fd8\u8981\u62c5\u5fc3\u9c7c\u523a\u7684\u95ee\u9898\uff1b\u8fd8\u6709\u4e9b\u4eba\u53ef\u80fd\u5c31\u4e0d\u7231\u5403\u9c7c\u3002\u6240\u4ee5\uff0c\u5982\u679c\u65e5\u5e38\u751f\u6d3b\u4e2d\u786e\u5b9e\u9c7c\u867e\u5403\u5f97\u4e0d\u591f\uff0c\u5403\u70b9\u9c7c\u6cb9\u5c31\u662f\u4e00\u79cd\u7b80\u5355\u53c8\u65b9\u4fbf\u7684\u65b9\u5f0f\u4e86\u3002<\/p>\n\n\n\n

\u5230\u5e95\u5982\u4f55\u9009\u62e9\u9c7c\u6cb9\u5462\uff1f<\/strong><\/p>\n\n\n\n

\u3000\u3000\u5e02\u573a\u4e0a\u7684\u9c7c\u6cb9\u4ea7\u54c1\u79cd\u7c7b\u5f88\u591a\uff0c\u5230\u5e95\u5982\u4f55\u9009\u62e9\u5462\uff1f\u5efa\u8bae\u5927\u5bb6\u5728\u9009\u62e9\u7684\u65f6\u5019\u6ce8\u610f\u51e0\u70b9\uff1a<\/p>\n\n\n\n

\u3000\u30001 \u9009\u62e9\u6b63\u89c4\u6e20\u9053\u548c\u54c1\u724c\u4ea7\u54c1<\/p>\n\n\n\n

\u3000\u3000\u5c3d\u91cf\u5728\u6b63\u89c4\u8d85\u5e02\u3001\u7535\u5546\u5e73\u53f0\u9009\u62e9\u5927\u54c1\u724c\u7684\u4ea7\u54c1\uff0c\u4e00\u822c\u66f4\u53ef\u9760\u3002<\/p>\n\n\n\n

\u3000\u30002 \u6ce8\u610f\u533a\u5206\u9c7c\u6cb9\u548c\u9c7c\u809d\u6cb9<\/p>\n\n\n\n

\u3000\u3000\u201c\u9c7c\u6cb9\u201d\u8ddf\u9c7c\u809d\u6cb9\u662f\u4e0d\u4e00\u6837\u7684\u3002\u9c7c\u809d\u6cb9\u7684\u4e3b\u8981\u6210\u5206\u662f\u7ef4\u751f\u7d20A\u548c\u7ef4\u751f\u7d20D\uff0c\u5f88\u591a\u5bb6\u957f\u60f3\u8981\u7ed9\u5b69\u5b50\u8865\u5145\u7ef4\u751f\u7d20A\u548c\u7ef4\u751f\u7d20D\u6765\u9884\u9632\u4f5d\u507b\u75c5\uff0c\u5e94\u8be5\u9009\u9c7c\u809d\u6cb9\uff1b\u800c\u82e5\u60f3\u8981\u8865\u5145DHA \uff0c\u8981\u6ce8\u610f\u9009\u9c7c\u6cb9\u3002<\/p>\n\n\n\n

\u3000\u30003 \u67e5\u770b\u4ea7\u54c1\u6d53\u5ea6<\/p>\n\n\n\n

\u3000\u3000\u9c7c\u6cb9\u4e2d\u6700\u91cd\u8981\u7684\u6307\u6807\u5c31\u662fEPA\u548cDHA\uff0c\u5f88\u591a\u4eba\u5728\u9009\u62e9\u7684\u65f6\u5019\u53ea\u770bEPA\u548cDHA\u7684\u542b\u91cf\uff0c\u4e5f\u8981\u770b\u6d53\u5ea6\uff0c\u770b\u4e00\u7c92\u9c7c\u6cb9\u4e2dEPA+DHA\u7684\u542b\u91cf\u3002\u4e00\u822c\u6765\u8bf4\uff0c\u6d53\u5ea6\u8d8a\u9ad8\u4ea7\u54c1\u8d28\u91cf\u8d8a\u597d\u3002<\/p>\n\n\n\n

\u3000\u3000\u6bd4\u5982\uff0c\u4e00\u9897\u9c7c\u6cb9\u662f1000mg\uff0c\u5176\u4e2d\u03c9-3\u8102\u80aa\u9178\u542b\u91cf 600mg(DHA500mg\uff0cEPA 100mg)\uff0c\u800c\u6709\u4e9b\u9c7c\u6cb9\u867d\u7136\u770b\u4e0a\u53bb\u6bcf\u9897\u7684\u4e2a\u5934\u5927\u4e00\u4e9b\uff0c\u4f46\u03c9-3\u8102\u80aa\u9178\u542b\u91cf\u4e5f\u53ef\u80fd\u66f4\u5c11\u3002\u5927\u5bb6\u9700\u8981\u4ed4\u7ec6\u5bf9\u6bd4\u4e00\u4e0b\u3002<\/p>\n\n\n\n

\u3000\u30004 \u770b\u5242\u91cf\uff0c\u9002\u91cf\u5403<\/p>\n\n\n\n

\u3000\u3000\u4e00\u822c\u8ba4\u4e3a\u666e\u901a\u6210\u4eba\u6bcf\u5929\u53ea\u9700\u8981200\u6beb\u514bDHA\uff0c\u5b55\u671f\u6bcf\u5929DHA+EPA\u7684\u6444\u5165\u91cf\u4e3a250 mg\uff0c\u5176\u4e2d\uff0cDHA\u81f3\u5c11200mg\u3002\u5927\u5bb6\u8981\u6839\u636e\u4ea7\u54c1\u6d53\u5ea6\u3001\u5242\u91cf\u9002\u91cf\u98df\u7528\u3002<\/p>\n\n\n\n

\u3000\u3000\u867d\u7136 DHA+EPA \u7684\u5b89\u5168\u8303\u56f4\u5f88\u5e7f\uff0c\u6bcf\u5929\u6444\u51652\u514b\u90fd\u662f\u5b89\u5168\u7684\uff0c\u4e0d\u7528\u592a\u62c5\u5fc3\u6709\u4ec0\u4e48\u5b89\u5168\u95ee\u9898\uff0c\u4f46\u9c7c\u6cb9\u6bd5\u7adf\u4e5f\u662f\u8102\u80aa\u3002\u5403\u591a\u5c11\u514b\u9c7c\u6cb9\uff0c\u8fd8\u8981\u4ece\u996e\u98df\u4e2d\u51cf\u6389\u591a\u5c11\u8102\u80aa\uff0c\u4fdd\u8bc1\u81b3\u98df\u5e73\u8861\u3002<\/p>\n\n\n\n

\u3000\u3000\u800c\u4e14\uff0c\u4e70\u56de\u5bb6\u7684\u9c7c\u6cb9\uff0c\u4e00\u65e6\u6253\u5f00\u62c6\u5c01\u4e86\uff0c\u5c31\u8981\u5c3d\u5feb\u5403\u5b8c\uff0c\u5403\u4e0d\u5b8c\u8981\u5c3d\u91cf\u653e\u5728\u9634\u51c9\u907f\u5149\u7684\u5730\u65b9\u5b58\u653e\uff0c\u9632\u6b62\u56e0\u4e3a\u5149\u7167\u3001\u9ad8\u6e29\u7b49\u5f71\u54cd\u5bfc\u81f4\u8102\u80aa\u9178\u6c27\u5316\u9178\u8d25\u3002<\/p>\n\n\n\n

\u3000\u3000\u603b\u4f53\u6765\u8bf4\uff0c\u9c7c\u6cb9\u4e0d\u80fd\u88ab\u795e\u8bdd\uff0c\u4e5f\u4e0d\u80fd\u88ab\u5b8c\u5168\u5426\u5b9a\u3002\u4f46\u5bf9\u4e8e\u5927\u591a\u6570\u4eba\u800c\u8a00\uff0c\u5982\u679c\u80fd\u901a\u8fc7\u5747\u8861\u7684\u996e\u98df\uff0c\u591a\u5403\u5bcc\u542b\u03c9-3\u8102\u80aa\u9178\u7684\u9c7c\u7c7b\u6c34\u4ea7\u54c1\uff0c\u4fdd\u8bc1\u8425\u517b\u7684\u6444\u5165\uff0c\u90a3\u81ea\u7136\u662f\u6700\u597d\u7684\u3002<\/p>\n\n\n\n

\u3000\u3000\u5982\u679c\u56e0\u4e3a\u5404\u79cd\u539f\u56e0\u65e0\u6cd5\u5403\u8db3\u591f\u9c7c\u7c7b\u6c34\u4ea7\u54c1\uff0c\u4e5f\u53ef\u4ee5\u9002\u5f53\u5403\u4e00\u4e9b\u9c7c\u6cb9\u3002\u9009\u8d2d\u65f6\u8981\u8c28\u614e\u591a\u770b\uff0c\u4e0d\u8981\u76f2\u76ee\u8ddf\u98ce\u8d2d\u4e70\u90a3\u4e9b\u5938\u5927\u5ba3\u4f20\u7684\u4ea7\u54c1\uff0c\u6700\u597d\u5728\u533b\u751f\u6216\u4e13\u4e1a\u8425\u517b\u5e08\u7684\u6307\u5bfc\u4e0b\u8fdb\u884c\u3002<\/p>\n\n\n\n

\u3000\u3000\u53c2\u8003\u6587\u732e<\/strong><\/p>\n\n\n\n

\u3000\u3000[1] Kwak SM, Myung SK, Lee YJ, Seo HG; Korean Meta-analysis Study Group. Efficacy of omega-3 fatty acid supplements (eicosapentaenoic acid and docosahexaenoic acid) in the secondary prevention of cardiovascular disease: a meta-analysis of randomized, double-blind, placebo-controlled trials. Arch Intern Med. 2012 May 14;172(9)\uff1a686-94. doi: 10.1001\/archinternmed.2012.262. PMID: 22493407.<\/p>\n\n\n\n

\u3000\u3000[2] Evangelos C. Rizos, et al .Association Between Omega-3 Fatty Acid Supplementation and Risk of Major Cardiovascular Disease Events A Systematic Review and Meta-analysis. JAMA. 2012;308(10)\uff1a1024-1033. doi:10.1001\/2012.jama.11374<\/p>\n\n\n\n

\u3000\u3000[3] Aung T,et al. Associations of Omega-3 Fatty Acid Supplement Use With Cardiovascular Disease Risks: Meta-analysis of 10 Trials Involving 77\u202f917 Individuals.JAMA Cardiol. 2018 Mar 1;3(3)\uff1a225-234.<\/p>\n\n\n\n

\u3000\u3000[4] Manson JE, Cook NR, Lee IM, Christen W, Bassuk SS, Mora S, Gibson H, Albert CM, Gordon D, Copeland T, D’Agostino D, Friedenberg G, Ridge C, Bubes V, Giovannucci EL, Willett WC, Buring JE; VITAL Research Group. Marine n-3 Fatty Acids and Prevention of Cardiovascular Disease and Cancer. N Engl J Med. 2019 Jan 3;380(1)\uff1a23-32. doi: 10.1056\/NEJMoa1811403. Epub 2018 Nov 10. PMID: 30415637; PMCID: PMC6392053.<\/p>\n\n\n\n

\u3000\u3000[5] Abdelhamid AS, Brown TJ, Brainard JS, et al. Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease. Cochrane Database of Systematic Reviews. 2020;(3)\uff1aCD003177. Accessed at cochranelibrary.comLink to External Link Policy on November 11, 2023.<\/p>\n\n\n\n

\u3000\u3000[6] Harris E. Fish Oil Pills Associated With Increased Risk of Heart Problems in Healthy People. JAMA. 2024;332(2)\uff1a97. doi:10.1001\/jama.2024.10340<\/p>\n\n\n\n

\u3000\u3000[7] Omega-3 acid ethyl esters – containing medicinal products for oral in use in secondary prevention after myocardial infarction[EB\/OL]. (2019-02-01) [2022-06-01].<\/p>\n\n\n\n

\u3000\u3000https: \/\/www. ema. europa. eu\/en\/medicines\/human\/referrals\/omega-3-acid-ethyl-esters-containingmedicinal-products-oral-use-secondary-prevention-after.<\/p>\n\n\n\n

\u3000\u3000[8] Omega-3 Fatty Acids. Fact Sheet for Consumers https:\/\/ods.od.nih.gov\/factsheets\/Omega3FattyAcids-Consumer\/https:\/\/ods.od.nih.gov\/factsheets\/Omega3FattyAcids-Consumer\/<\/p>\n\n\n\n

\u3000\u3000[9] Eric B. Rimm,et al. Seafood Long-Chain n-3 Polyunsaturated Fatty Acids and Cardiovascular Disease: A Science Advisory From the American Heart Association. Circulation. 2018;May 17.<\/p>\n\n\n\n

\u3000\u3000[10] Omega-3\u8102\u80aa\u9178\u5728\u5fc3\u8840\u7ba1\u75be\u75c5\u9632\u6cbb\u4e2d\u7684\u4f5c\u7528\u4e2d\u56fd\u4e13\u5bb6\u5171\u8bc6[J].\u4e2d\u56fd\u5faa\u73af\u6742\u5fd7\uff0c2023,38(02)\uff1a116-130.<\/p>\n\n\n\n

\u3000\u3000[]https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2009\/021654s023lbl.pdf<\/p>\n\n\n\n

\u3000\u3000[11] \u4e2d\u56fd\u5c45\u6c11\u81b3\u98df\u8425\u517b\u7d20\u53c2\u8003\u6444\u5165\u91cf(DRIs)2023.<\/p>\n\n\n\n

\u3000\u3000[12] https:\/\/www.nccih.nih.gov\/health\/omega3-supplements-what-you-need-to-know<\/p>\n\n\n\n

\u3000\u3000[13] \u4e2d\u56fd\u5c45\u6c11\u81b3\u98df\u6307\u53572022.<\/p>\n\n\n\n

\u3000\u3000\u7b56\u5212\u5236\u4f5c<\/p>\n\n\n\n

\u3000\u3000\u4f5c\u8005\u4e28\u962e\u5149\u950b \u79d1\u4fe1\u98df\u54c1\u4e0e\u5065\u5eb7\u4fe1\u606f\u4ea4\u6d41\u4e2d\u5fc3\u526f\u4e3b\u4efb \u4e2d\u534e\u9884\u9632\u533b\u5b66\u4f1a\u5065\u5eb7\u4f20\u64ad\u5206\u4f1a\u59d4\u5458<\/p>\n\n\n\n

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